What if two carriers of mutations in the same disease gene want to have children together?
If two partners are carriers of a gene mutation for the same disease, then, with each pregnancy, there is a 1 in 4 chance of having an affected child, there is a 2 in 4 chance of having a child who is an asymptomatic (healthy) carrier, and a 1 in 4 chance of having a child who is neither a carrier nor affected.
