What if the Quad Fetal Risk Assessment suggests an increased risk for Neural Tube Defects?
Elevated AFP levels can be seen in several conditions such as neural tube defects (NTD), pregnancies farther along than expected, more than one baby, and babies with certain other complications. Neural Tube Defects A neural tube defect (NTD) is an abnormal opening of the skull or spine resulting from a developmental difficulty very early in pregnancy. One or two babies in 1,000 are born with an NTD with no prior family history. When there is a family history of NTD or an exposure which increases risks for NTD, more direct forms of prenatal diagnosis may be indicated. The Quad assessment will identify 85% of all pregnancies involving an open neural tube defect. This early warning permits health care providers and families to plan for appropriate management at delivery and after birth. If gestational age, presence of one baby, and no observable problems are confirmed by ultrasound, the health care provider may suggest repeating the test. Slightly less than 3 out of 4 (70%) women who have
