What Health Studies Have Been Done on Synthetic Amorphous Silica?
The United Nation’s Organization for Economic Co-operation and Development (OECD) has been characterizing the hazardous properties of High Production Volume (HPV) chemicals. The “Screening Information Data Set” (SIDS) for synthetic amorphous silica was released in 2004. The SIDS report concluded that synthetic amorphous silica (SAS) is a low priority for further study. Excerpts from the OECD SIDS Human Health conclusions are included below1: Absorption, disposition, elimination: SAS forms [CAS No 7631-86-9] are rapidly eliminated from the lung tissue during and after prolonged inhalation exposure of experimental animals with no disproportionate disposition occurring in the mediastinal lymph nodes, whereas crystalline forms exhibit a marked tendency to accumulate and persist in the lung and lymph nodes. Intestinal absorption of SAS appears to be insignificant in animals and humans. There is evidence of ready renal elimination of bioavailable fractions. Acute toxicity: Following inhalati
