What happens when GA-1 is treated?
With prompt and lifelong treatment, children with GA-1 can often live healthy lives with typical growth and learning. Early treatment can help prevent episodes of metabolic crisis and the resulting health effects. Even with treatment, some children continue to have episodes of metabolic crisis. This can lead to brain damage and long-term problems with involuntary movements and spasticity. After age six, metabolic crises are less common.