What happens if I use products containing salicylates while taking guaifenesin?
If it completely blocks the action of Guai, reversal of your FMS symptoms will cease and you will regress into the condition once again. If you partially block reversal time will be extended. The good effects of guaifenesin are very easily blocked by aspirin (a salicylate) in its many hidden forms. Tiny, tiny amounts on the skin will do this.