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What genes are responsible for tuberous sclerosis complex?

April 26, 2017complex genes responsible sclerosis tuberous

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What genes are responsible for tuberous sclerosis complex?

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Two genes have been identified that can cause tuberous sclerosis complex. Only one of the genes needs to be affected for tuberous sclerosis complex to be present. The TSC1 gene is located on chromosome 9 and is called the hamartin gene. The other gene, TSC2, is located on chromosome 16 and is called the tuberin gene. Researchers are now trying to determine what these genes do and how a defect in these genes causes tuberous sclerosis complex.