What effect does CHB have on the cancer and how does its inclusion support the SI procedure?
Complete hormonal blockade (CHB) results in significant cancer cell death. It also reduces the number of normal cells. It unfortunately does not kill all the cancer cells. Since radiation is more effective when there are fewer number of cells it needs to kill, CHB is attractive as additional treatment, especially in those situations in which there is a bulky cancer or a high chance of disease outside the gland. The morbidity of CHB is relatively low and short term compared to, for example, chemotherapy.
