What drugs are FDA-approved for postexposure prophylaxis (PEP) and treatment?
Ciprofloxacin and doxycycline are FDA-approved for PEP, and ciprofloxacin, doxycycline, and amoxicillin are FDA-approved for treatment. In the current situation of intentional anthrax distribution, doxycycline and ciprofloxacin are the recommended drugs for prophylaxis. Inhalational anthrax treatment protocol for cases associated with this bioterrorism attack: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5042a1.htm – (table 1) Cutaneous anthrax treatment protocol for cases associated with this bioterrorism attack: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5042a1.htm – (table 2) Who should receive antibiotics for 60 days? People at risk for inhalational anthrax should receive 60 days of antibiotics. These people include the following: • People who have been exposed to an air space known to have been contaminated with aerosolized B. anthracis. • People who share the air space within a facility where others have acquired inhalational anthrax. • People who have been along the transit pathwa