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• TUMOR NECROSIS FACTOR (noun) The noun TUMOR NECROSIS FACTOR has 1 sense: 1. a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis) Familiarity information: TUMOR NECROSIS FACTOR used as a noun is very rare.
