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• TRNA (noun) The noun TRNA has 1 sense: 1. RNA molecules present in the cell (in at least 20 varieties, each variety capable of combining with a specific amino acid) that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell (according to directions coded in the mRNA) Familiarity information: TRNA used as a noun is very rare.
