What does the Research Literature say?
In their 2008 literature review on the use on the use of atypical antipsychotics in anorexia nervosa of children and adolescents, Mehler-Wex, Romanos, Kircheiner and Shulze present preliminary conclusions on both olanzapine and quetiapine. The authors indicate that there is data supporting the notion that olanzapine seems to be effective in the psychopathology associated with anorexia and report no significant adverse side effects. Due to the tendency for olanzapine to increase appetite, the main challenge of olanzapine (105) is compliance. Mehler-Wex and his colleagues indicate that quetiapine might be more favorable to patients because of its lower propensity to induce weight gain. While they make no specific conclusions, namely due to the lack of research on its efficacy in children in adolescents, the authors suggest that quetiapine could be a potentially promising option for this age group, given the favorable outcomes found in studies on adults (Mehler-Wex et al., 2008). Another
