What does the FDA say about methadone?
On November 26, 2007, the FDA issued an advisory warning of potential fatal outcomes associated with methadone. The agency warned that “prescribing methadone is complex” because its analgesia wears off long before it is cleared from the body. The announcement coincided with new prescribing guidelines, which lowered the maximum suggested initiation dosage from 80 mg to 30 mg per day.
