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• HEMATOCRIT (noun) The noun HEMATOCRIT has 2 senses: 1. the ratio of the volume occupied by packed red blood cells to the volume of the whole blood as measured by a hematocrit 2. a measuring instrument to determine (usually by centrifugation) the relative amounts of corpuscles and plasma in the blood Familiarity information: HEMATOCRIT used as a noun is rare.
