What does finasteride or dutasteride do to my PSA?
You should multiply your PSA value by 2 or 2.3 if you are taking a drug like finasteride (Proscar) or dutasteride (Avodart) and use this adjusted value to make decisions such as whether to have prostate biopsies or not. These drugs lower PSA and an adjustment must be made for correct interpretation. When on these medications, most of the change in PSA is due to prostate cancer, if present, and so changes in PSA are more important.