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• ATROPINE (noun) The noun ATROPINE has 1 sense: 1. a poisonous crystalline alkaloid extracted from the nightshade family; used as an antispasmodic and to dilate the eye pupil; also administered in large amounts as an antidote for organophosphate nerve agents or organophosphate insecticides Familiarity information: ATROPINE used as a noun is very rare.
