What does an elevated gastrin level indicate?
Gastrin is a hormone produced by G cells in the stomach that stimulate the production of gastric acid. Different conditions may result in increased levels of gastrin: e.g. patients with pernicious anemia, atrophic gastritis, renal insufficiency, gastric outlet obstruction, medications that block gastric acid production (H2 blockers and proton pump inhibitors), and a neuroendocrine tumor called Zollinger Ellison that may be located in the pancreas.