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What does Added by Computer in the mutation comments box signify?

April 26, 2017added Box comments Computer mutation

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What does Added by Computer in the mutation comments box signify?

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The software adds mutations in two different instances: a. When the dropping factor of a mutation is > .15 and the intensity is >500, yet the score does not meet the detection threshold of 5.00, the software adds this mutation, because the low score is most likely due to mobility shift. b. When the data is noisy, but the frequency of the mutation is high (>10%).