What does a change in liver function tests (LFTs) mean?
A change in LFTs is only one finding that may suggest liver problems. These tests will be repeated over time. Your doctor or nurse may also order a scan that looks at your liver and spleen. LFTs that remain high, and knowing whether your liver is enlarged, will help your doctor or nurse figure out the source of the problem and decide on the best treatment. What is the treatment for liver problems? There are many sources of liver problems in people with CF. Once the source has been figured out, your doctor or nurse may prescribe an oral medicine or a special diet. One of the most common drugs used is Ursodiol (pronounced er–so-DI-all). This pill is taken one to three times a day to help increase bile flow which improves liver function. Side effects, which are rare, consist of itching and diarrhea. In a very small number of people with CF who have severe liver disease, a liver transplant may be needed. Checking for liver disease before symptoms occur is the best practice. The CF Clinical
