What Do We Currently Know About the Basic Health and Environmental Hazards of HPV Chemicals?
The information relevant to understanding the basic health and environmental hazards of HPV chemicals is derived from a battery of tests agreed upon by the international community as appropriate for screening international HPV chemical substances for toxicity. Six basic testing endpoints have been adopted by the Organization for Economic Cooperation and Development (OECD) as the minimum required to screen international HPV chemical substances for toxicity (Ref. 4). The agreed-upon testing endpoints, known as the OECD’s Screening Information Data Set (SIDS) include: Acute toxicity; repeat dose toxicity; developmental and reproductive toxicity; genetic toxicity (gene mutations and chromosomal aberrations); ecotoxicity (studies in fish, Daphnia, and algae); and environmental fate (including physical/ chemical properties [melting point, boiling point, vapor pressure, n-octanol/water partition coefficient, and water solubility], photolysis, hydrolysis, transport/distribution, and biodegrada
