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What distinguishes an NIH Roadmap Transformative Research Project Award from a standard R01?

April 26, 2017award distinguishes NIH project R01 Research roadmap standard transformative

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What distinguishes an NIH Roadmap Transformative Research Project Award from a standard R01?

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The Roadmap Transformative Research Program is different in several ways. First, it is designed to support high risk research that will create new or challenge existing paradigms. It is expected that Transformative projects will reflect an exceptional level of creativity in proposing bold and highly innovative new approaches to fundamental problems. Anticipated research outcomes must have a major impact on broad, important problems in biomedical and/or behavioral research, or lead to major improvements in health through the development of highly innovative therapies, diagnostic tools, or preventive strategies. Proposals from any/all areas of science relevant to the NIH mission will be considered for support under the Roadmap Transformative Research Projects program (http://www.nih.gov/about/almanac/).