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What defines “invasive” group A streptococcal disease?

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What defines “invasive” group A streptococcal disease?

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A case of invasive disease is confirmed when GAS is isolated from a normally sterile site, such as blood. When GAS is cultured from a nonsterile wound from a patient with necrotizing fasciitis or streptococcal toxic shock syndrome, this is also considered evidence of invasive GAS disease.

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