What content is on an array from the TF Chip MAPK Kit?
MAPK (= mitogen activated protein kinases) build intracellular signaling cascades that regulate major cellular functions such as growth, differentiation, immune-mediated inflammatory responses, stress responses and apoptosis. There are four main cascades involved: the extracellular signal regulated kinases (ERK1/2 and ERK5) or the stress activated protein kinases (p38/SAPK2 and JNK/SAPK). The content of TF Chip MAPK arrays is: c-Jun, ATF-2, c-Myc, Elk-1, MEF2, NFATc1, p53, STAT1.