What cells are affected by post-thaw cell death?
The cells farthest from the catheter tip but still within the freeze zone may succumb to necrosis or apoptosis. Only cells that have been stressed in some way by the freezing process can be destroyed post-thaw. Necrosis and apoptosis are events that complete the CryoAblation process by filling in the periphery of the lesion. They do not cause new cell damage and do not increase the size of lesion.