What causes vein valves to malfunction leading to venous reflux and backflow?
• Birth-related or Familial (inherited “weak” veins). • Hormone changes related to birth control or pregnancy. This causes the vein to enlarge and increases pooling of blood within leg veins damaging the valve. • History of blood clot resulting in damaged vein and valve. • Pelvic obstruction from a mass or pregnancy physically blocks the return of venous blood and damages the valve. • Gravity – Occupations requiring long periods of standing also increase pooling of blood within leg veins causing damage to the vein’s valve. Venous reflux is commonly seen in teachers, nurses, retail business, and factory workers.
