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What causes Polycythemia Vera?

April 26, 2017causes mn_whatis Polycythemia Vera

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What causes Polycythemia Vera?

2 Answers

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Polycythemia vera (PV) also is known as primary polycythemia. A mutation, or change, in the body’s JAK2 gene is the main cause of PV. The JAK2 gene makes an important protein that helps the body produce blood cells. What causes the change in the JAK2 gene isn’t known. PV generally isn’t passed from parent to child. However, in some families, the JAK2 gene may have a tendency to mutate. Other, unknown genetic factors also may play a role in causing PV.

0

Posted

Polycythemia vera (PV) also is known as primary polycythemia. A mutation, or change, in the body’s JAK2 gene is the main cause of PV. The JAK2 gene makes a protein that helps the body produce blood cells. What causes the change in the JAK2 gene isn’t known. PV generally isn’t inherited that is, passed from parents to children through genes. However, in some families, the JAK2 gene may have a tendency to mutate. Other, unknown genetic factors also may play a role in causing PV.