What causes Ph+ CML?
When a person is healthy, signals in the body tell it to produce new blood cells. These signals reach early cells, called stem cells, which mature into various types of blood cells. The signals turn stem cells on and off as necessary to produce the number of blood cells the body needs. When a person has CML, a change takes place in the person’s DNA and makes this signal stay on constantly. Since this signal stays on, the body produces more and more abnormal cells.
