What causes lung cancer in non-smokers?
Non-smoking Lung Adenocarcinoma: Causative factors. Funding year: 2007 Amount funded: $94,746 Lead researcher: Ms Jill Larsen BSc(Hons) Research team: Assoc Prof Kwun Fong MBBS(Lon) FRACP, PhD Dr Rayleen Bowman MBBS, FRACP, Grad Cert Med Ed Dr Ian Yang MBBS, FRACP, PhD, Grad Dip Med Epi Dr Belinda Clarke MBBS, FRACP, PhD, Grad Cert Med Ed Location of research: The Prince Charles Hospital, 627 Rode Road, Chermside, Queensland Project description: As tobacco smoking reduces in our population, there is an increasing burden of disease from lung cancers in never-smokers. Nowadays, it is not uncommon, and a difficult clinical management scenario, to diagnose lung cancer in younger people who have never smoked. The aims of this project are to identify the unique structural and functional gene profiles in never-smoking adenocarcinomas to build novel therapies. Discovering the critical DNA and RNA aberrations that occur in never smoking lung cancer will help to define the biological pathways im