What Causes Low Alkaline Phosphatase?
Alkaline phosphatase is an enzyme involved in many chemical reactions in the body. Primarily concentrated in the liver and bones, alkaline phosphatase levels are generally evaluated as part of a liver function laboratory test. Elevated levels may indicate damage or disease of the liver, or bone diseases such as osteomalacia or Paget’s disease. Although rare, low levels of alkaline phosphatase may occur and are generally due to genetic conditions or nutritional deficiencies.
