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What causes large bubbles within the dialyzer following reprocessing?

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What causes large bubbles within the dialyzer following reprocessing?

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A. RENALIN Cold Sterilant will produce oxygen gas when it is exposed to residual blood products remaining in a dialyzer after it has been used. To reduce this phenomenon, you may consider using the pre-clean cycle on the RENATRON II System. You may also wish to analyze the dialyzer handling practices in your dialysis unit that may influence the amount of clotting that may occur during and after a dialysis treatment.

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