What causes heparin-induced thrombocytopenia?
It is thought that problems in the body’s immune system may cause Type 2 HIT. The immune system is the part of the body that fights infection. Normally, the immune system makes antibodies (substances) that destroy foreign substances and germs, such as viruses and bacteria. With Type 2 HIT, antibodies stick to a heparin and platelet complex and cause more blood clots to form. A heparin and platelet complex is where heparin hooks onto a platelet. The following may put you at a higher risk of getting HIT: • Having an intravenous line (IV) or a central line that is flushed with heparin, or a heparin-coated central line. • Receiving bovine heparin (from a cow) rather than porcine heparin (from a pig). • Receiving unfractionated heparin, or receiving low-molecular-weight heparin after receiving unfractionated heparin. • Recent blood vessel procedures. • Recent surgery, including heart surgery and bone surgery, such as a hip replacement. What are the signs and symptoms of heparin-induced thro
