What causes Chagas disease to be called a vicious cycle?
First, as current estimates of Chagas disease prevalence rates are based on incomplete data, the scope of treatment needs is not evident. Without up-to-date, evidence-based reporting of disease prevalence and patient needs, there is little incentive to engage in research and development for new drugs and diagnostics. Investments to support targeted epidemiological studies are needed to generate a more accurate estimate of Chagas disease prevalence and incidence in Latin America, which can then stimulate the development of new health tools for Chagas disease. The second vicious cycle refers to the cycle of poverty. Chagas affects predominantly poor populations, and results in significant disability that often leads to unemployment, decreased earning ability and increased costs in order to access treatment. As a result, Chagas disease patients often remain poor and they and their families continue to live in conditions that promote the spread of the disease and perpetuate this cycle.