What causes acquired von Willebrand syndrome?
The following are possible causes and conditions that may increase your risk of having AVWS: • Diseases: The VWF may stick or attach itself to cancer (tumors), such as in leukemia, lymphomas, or kidney tumors. This will decrease the amount of VWF going around in the body. Certain diseases, such as scleroderma, lupus, or heart diseases, may also increase your risk. VWF is decreased or absent in hypothyroidism. Hypothyroidism is a condition where the thyroid gland produce little thyroid hormone (chemical) which helps release VWF. • Immune problems: The immune system is the part of your body that fights infection. A problem with the immune system sometimes makes your body attack its own cells. This may make you more likely to develop AVWS. • Medicines: Medicines used to treat cancer, depression, or infections may cause AVWS. Ask your caregiver for information about these medicines. • Toxic chemicals: Frequent exposure to toxic chemicals, such as pesticides, may increase your risk of havin