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What causes a low production of intrinsic factor?

April 26, 2017anaemia b12 vitamin blood causes Factor intrinsic low production red tongue tiredness

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What causes a low production of intrinsic factor?

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• Antibodies can form against the cells that produce intrinsic factor. The cells then die, leading to B12 deficiency and anaemia. • Stomach cancer and ulcers can take up so much room in the stomach that there are too few cells left to produce intrinsic factor. • Diseases of the small intestine, fish tapeworm and the after-effects of bowel surgery can all result in the surface of the small intestine being too small to absorb B12 and intrinsic factor effectively.