What can cause an inhomogenous spleen in hodgkin lymphoma?
My friend has Hodgkin lymphoma and his disease has gone away in his chest but he still has tiny densities and mild inhomogenity on his spleen. He is done with chemotherapy. What does it mean to have inhomogenous stuff on the spleen? Is it like a scar? A: This is a term used by radiologists that does not help us much as clinicians because it is so non-specific. It probably means nothing. We can’t safely biopsy the spleen – it bleeds too easily. If the Hodgkin’s lymphoma has resolved in the chest, it is not very likely that the lymphoma is active in the “inhomogeneous” areas of the spleen. To really know what is going on in the spleen, you would have to surgically remove it. This will not be recommended with an uncertain report stating “inhomogeneous.” Follow-up and time are the key. There is no better test in this situation than the “test of time” to see if your friend has a durable remission. There is no great hurry to find recurrence. I would assume a positive outlook. We do well trea
