What biospecimens are collected on EAGLE participants?
Subjects contributed blood (which is divided into various components for storage including serum, plasma, buffy coat, red blood cells, DNA, RNA, whole blood, and blood cards) or, in rare occasions, buccal cell samples. Tissue blocks, tissue slides, and fresh tissue (frozen in liquid nitrogen) were obtained from operative candidates. The proportion of subjects from whom genetic material is available is close to 100%.