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What are vasodilators and nitrates?

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What are vasodilators and nitrates?

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Vasodilators are a class of medications that cause blood vessels to widen (dilate). Nitrates are the most common type of vasodilator medication. They are sometimes given to women with heart failure to relieve symptoms that persist after treatment with the standard medications. Nitrates are also combined with the high blood pressure drug hydralazine in a single pill to treat heart failure in African-Americans who are already receiving a beta-blocker and either an ACE inhibitor or ARB. African Americans may not respond as well as whites to ACE inhibitors, the first-choice blood pressure drugs for heart failure, which is why additional medication may be needed in these patients. This combination of nitrates and hydralazine may also be used in other patients who have symptoms despite standard treatment. Hydralazine is used together with nitrates because nitrates widen the veins and hydralazine widens the arteries, making the combination more effective than either drug alone. Hydralazine ma

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