What Are the Types of Mature B-Cell Lymphoma?
Diffuse large B-cell lymphoma is the most common non-Hodgkin’s lymphoma. The majority of cases include enlarged lymph nodes that can be accompanied by symptoms such as fatigue, fevers, sweats, or weight loss. Approximately one-third of the patients with this disease will have the lymphoma appear in an organ other than lymph nodes. Essentially any organ in the body can be involved. The gastrointestinal tract is a common site for diffuse large B-cell lymphoma to be found, but lung, kidney, brain, testicle, liver, skin, bones, thyroid, etc. can be the initial site of the disease. Three specific situations deserve special mention: (1) Diffuse (nonfollicular) large B-cell lymphoma is the most common cancer in the testicles of men over 60. (2) It can also be a brain tumor. This is particularly likely in patients with severe immunosuppression (less ability to fight disease), such as those infected by human immunodeficiency virus (HIV); it is also found in patients with no preceding illness. F
