What are the symptoms of sickle cell anemia?
Virtually all of the major symptoms of sickle cell anemia are the direct result of the abnormally shaped sickled red blood cells blocking the flow of blood that circulates through the tissues of the body. The tissues with impaired circulation suffer damage from lack of oxygen. Damage to tissues and organs of the body can cause severe disability in patients with sickle cell anemia. The patients endure episodes of intermittent “crisis” of variable frequency and severity, depending on the degree of organ involvement. The major features of sickle cell anemia include: Tiredness and anemia Pain crises Swelling and inflammation of the hands and/or feet Bacterial infection Sudden pooling of blood in the spleen Lung and heart injury Leg ulcers Death of portions of bone Eye damage Anemia and Tiredness (Fatigue) Fatigue is a common symptom in persons with sickle cell anemia. The disease causes a chronic form of anemia which can lead to fatigue. The sickled red blood cells are prone to breakage (r
