What are the symptoms of autosomal dominant polycystic kidney disease?
ADPKD is usually an adult-onset condition. This means that many people with ADPKD live for decades without developing symptoms of renal functional decline. People who have ADPKD have renal cysts in both kidneys and may also develop cysts in other organs such as the liver and pancreas; abnormalities of blood vessels (vascular system) such as high blood pressure (hypertension) intracranial and aortic aneurysms, heart valve defects , and abdominal wall hernias. Hypertension is the most common problem as a result of ADPKD. About half of individuals who have ADPKD develop end-stage kidney disease by the age of 60.