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What are the steps of freeze-drying?

April 26, 2017freeze-drying steps

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What are the steps of freeze-drying?

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• Freezing • Primary drying or sublimation • Secondary drying or desorption The steps of the process will be dependent upon the nature of the product being lyophilized. The freeze-drying cycle parameters for each product will vary depending upon the freezing and drying behavior of each product. The success of the overall process is dependent upon proper definition and execution of each step. 3. What are the materials of construction for both the GORE™ LYOGUARD® Tray and Container? These completely enclosed, single-use, autoclavable lyophilization products are constructed of polypropylene and expanded polytetrafluoroethylene (ePTFE). The microporous ePTFE membrane is incorporated into the top surface of the tray and container, protecting the product inside from cross-contamination and reducing fly-out. The tray has a convenient fill port and the container has a removable screw-top for ease of filling. The flexible, thin-film polypropylene bottom closely conforms to dryer shelves for eff

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Lyophilization involves three major steps. They are pretreatment, freezing, and drying which includes primary drying (sublimation) and secondary drying (desorption). The parameters involved in freezing and drying steps can be customized for optimum lyophilization results.