What are the standard treatments for heart failure?
Most people with heart failure (systolic dysfunction) end up on ACE inhibitors and diuretics, digoxin and beta blockers. ACE Inhibitors prevent the production of a substance that causes blood vessels to tighten and raises blood pressure. As a result, blood pressure drops and the heart does not have to work as hard to pump blood. ACE Inhibitors also work directly on the heart. Diuretics help reduce the amount of fluid in the body and are useful for patients with fluid retention and hypertension. Digoxin increases the force of the heart’s contractions, which help to improve circulation. Beta blockers block the action of adrenaline, which the body produces under stress. The drugs reduce demand on the heart, slow the heart rate and prevent irregular heartbeats. We have a lot of experience with beta blockers. I was U.S. principal investigator of a study that showed that it improved survival. They have to be given very carefully and appropriately because they have a very good long-term effec
