What are the signs and symptoms of Hendra virus disease and Nipah virus encephalitis?
Only three human cases of Hendra virus disease have been recognized. Two of the three individuals known to be infected had a respiratory illness with severe flu-like signs and symptoms. Infection with Nipah virus was associated with an encephalitis (inflammation of the brain) characterized by fever and drowsiness and more serious central nervous system disease, such as coma, seizures, and inability to maintain breathing. Illness with Nipah virus begins with 3-14 days of fever and headache. This is followed by drowsiness and disorientation characterized by mental confusion. These signs and symptoms can progress to coma within 24-48 hours. Some patients have had a respiratory illness during the early part of their infections. Are there any complications after recovery? One of the three Hendra virus infections was marked by a delayed onset of progressive encephalitis. Serious nervous disease with Nipah virus encephalitis has been marked by some sequelae, such as persistent convulsions and
