What are the significant questions for continuing research?
To address these questions, the National Heart, Lung, and Blood Institute and the Office of Medical Applications of Research of the National Institutes of Health convened a Consensus Development Conference on Triglyceride, High Density Lipoprotein, and Coronary Heart Disease on February 26-28, 1992. After 2 days of presentations by experts and discussion by the audience, a consensus panel drawn from specialists and generalists from the medical profession and related scientific disciplines, clinical investigators, and public representatives considered the evidence and came to the following conclusions. Is the Relationship of High Triglyceride and/or Low HDL Levels With Coronary Heart Disease Causal? Associations between triglyceride, HDL, and coronary heart disease are well described in the literature. Causality may be inferred based on consistency of the data, strength of association, temporality, dose response, specificity, and biologic plausibility. The relevant observations for thes
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