What are the side effects of vaginal Premarin?
• A: Although the risk of a serious adverse effect is much less likely for most women using low doses of estrogens vaginally compared to orally, adverse effects are possible. Serious adverse effects of estrogen therapy include: breast cancer, cancer of uterus, stroke, heart attack, blood clots, dementia, and gallbladder disease. If you are predisposed to any of the above conditions because of family history, high cholesterol, high blood pressure, tobacco use, or obesity, you are at a higher risk for complications. The most common side effects of vaginal Premarin therapy are back pain; bloating; breast pain; depression; diarrhea; dizziness; flu syndrome; gas; hair loss; headache; cough; indigestion; infection; irregular vaginal bleeding or spotting; itching; joint pain; lightheadedness; leg cramps; muscle aches; nausea; nervousness; pain; runny nose; sinus inflammation; sleeplessness; sore throat; stomach pain; upper respiratory tract infection; vaginal inflammation; weakness; and weigh