What are the Side Effects of Topical Retinoids in Acne?
Because of their desquamatory effects on the superficial skin layers, topical retinoids may cause mild to moderate irritation in some patients. Some patients may experience the following: • A burning or stinging sensation may be felt after application, mostly in the initial weeks. • Slight redness of the facial skin may occur between the first and fifth weeks of application • Some patients may experience worsening of the acne during the second to third weeks of treatment with topical retinoids. This is due to an inflammatory blowup of hidden comedones and papules lying underneath and is actually an encouraging sign. • Photosensitization to sunlight and artificial light sources is common with topical retinoids.
