What are the side effects of proton pump inhibitors?
The proton pump inhibitors are relatively safe drugs. The most commonly observed adverse effects are constipation, diarrhea, dizziness, headache, skin itch, and skin rash. Less often, the following adverse effects have been reported: abdominal pain with cramps, appetite changes, and nausea. The following adverse effects are extremely rare but have been reported with this class of drugs: • acute pancreatitis • anxiety • cough • depression • drug toxin-related hepatitis • erythema multiforme • flu-like symptoms • myalgia • Stevens-Johnson syndrome • thrombocytopenia • toxic epidermal necrolysis • ulcerative colitis • upper respiratory hypersensitivity reaction • upper respiratory infection • vomiting Source: The Gale Group.