What are the side effects of antacids?
• Antacids may cause dose-dependent rebound hyperacidity and milk-alkali syndrome. • Antacids that contain aluminum hydroxide may cause constipation, aluminum-intoxication, osteomalacia, and hypophosphatemia. They also may cause rebound hyperacidity and milk-alkali syndrome. • Antacids that contain magnesium have a laxative effect that may cause diarrhea, and in patients with renal failure they may cause increased magnesium levels in the blood. With which drugs do antacids interact? When antacids are taken with acidic drugs such as [digoxin (Digitek), phenytoin (Dilantin), chlorpromazine (Thorazine), isoniazid], they cause the absorption of the acidic drugs to be decreased, which causes low blood concentrations of the drugs, which ultimately results in reduced effects of the drugs. Antacids taken with drugs such as [pseudoephedrine (Sudafed, Semprex D, Clarinex-D 12hr, Clarinex-D 24hr, , Deconsal, Entex PSE, Claritin D, and more), levodopa (Dopar)], increase absorption of the drugs and
