What are the side effects of AMRIX therapy?
In clinical trials, the most commonly reported adverse reactions (≥3%) with once-daily AMRIX were dry mouth, dizziness, fatigue, constipation, nausea, and dyspepsia. Less than 5% of patients taking once-daily AMRIX discontinued therapy due to an adverse reaction. AMRIX is closely related to tricyclic antidepressants, which have been reported to produce arrhythmias, sinus tachycardia, prolongation of the conduction time leading to myocardial infarction, and stroke. Because of its atropine-like action, AMRIX should be used with caution in patients with a history of urinary retention, angle-closure glaucoma, increased intraocular pressure, and in patients taking anticholinergic medication.
