What are the risks of using Depo-Provera?
Women who use contraceptives with hormones (like the Depo shot) have an increased risk of blood clots or stroke. There is also an increased chance of ectopic pregnancy meaning that the fetus develops outside the uterus. Although possible, these events are rare. Depo may cause bones to become thinner while you use the shot. This could increase your risk of a broken bone. It is important to get enough calcium in your diet while receiving Depo-Provera. When you stop taking Depo, your bones should return to their normal thickness.