What are the risks of barbiturate-induced coma?
An estimated 25% of barbiturate-induced comas are accompanied by severe side effects. The side effects of barbiturates, especially the depressive effect on the cardiovascular system, can be too risky for some patients. Other side effects include impaired gastrointestinal motility and impaired immune response and infection. Since barbiturates depress activity in the brain, measurements of brain activity may be unreliable. Careful monitoring of the patient is required to ensure nutritional needs are being met and to guard against complications, such as lung infection, fevers, or deep vein blood clots. Source: The Gale Group. Gale Encyclopedia of Medicine, 3rd ed.